QuickBooks Desktop Error 15222 plagues users who are attempting to download an update for their version of the QuickBooks Payroll or QuickBooks Desktop. It could be caused by your antivirus quarantining the update file as a trojan or malware, your Internet Explorer not having a matching digital security certificate, or having a different default browser from IE. Whatever be the issue, QuickBooks Error Support number will help you rectify it by identifying the root cause and completely eliminating the root cause. It’s toll-free 1-888-412-7852.

Source: https://qbdesktopsupport.com/how-to-resolve-quickbooks-error-code-15222/