By Fergus Walsh
Medical correspondent
23 April 2020
The first human trial in Europe of a coronavirus vaccine has begun in Oxford.
Two volunteers were injected, the first of more than 800 people recruited for the study.
Half will receive the Covid-19 vaccine, and half a control vaccine which protects against meningitis but not coronavirus.

The design of the trial means volunteers will not know which vaccine they are getting, though doctors will.

Elisa Granato, one of the two who received the jab, told the BBC: "I'm a scientist, so I wanted to try to support the scientific process wherever I can."

The vaccine was developed in under three months by a team at Oxford University. Sarah Gilbert, professor of vaccinology at the Jenner Institute, led the pre-clinical research.

"Personally I have a high degree of confidence in this vaccine," she said.

"Of course, we have to test it and get data from humans. We have to demonstrate it actually works and stops people getting infected with coronavirus before using the vaccine in the wider population."

Prof Gilbert previously said she was "80% confident" the vaccine would work, but now prefers not to put a figure on it, saying simply she is "very optimistic" about its chances..

So how does the vaccine work?
The vaccine is made from a weakened version of a common cold virus (known as an adenovirus) from chimpanzees that has been modified so it cannot grow in humans.

The Oxford team has already developed a vaccine against Mers, another type of coronavirus, using the same approach - and that had promising results in clinical trials.


How will they know if it works?
The only way the team will know if the Covid-19 vaccine works is by comparing the number of people who get infected with coronavirus in the months ahead from the two arms of the trial.

That could be a problem if cases fall rapidly in the UK, because there may not be enough data.

Prof Andrew Pollard, director of the Oxford Vaccine Group, who is leading the trial, said: "We're chasing the end of this current epidemic wave. If we don't catch that, we won't be able to tell whether the vaccine works in the next few months. But we do expect that there will be more cases in the future because this virus hasn't gone away."

The vaccine researchers are prioritising the recruitment of local healthcare workers into the trial as they are more likely than others to be exposed to the virus.

A larger trial, of about 5,000 volunteers, will start in the coming months and will have no age limit

Source: www.bbc.com/news/amp/health-52394485

Lalasticalala

One trial should jst work abeg, and am conviced this will work, but b4 it will be to thw poor mass it will take years

You up there!!!!You stole my spot.....
Meanwhile
.y

FastestGirl:
You up there!!!!You stole my spot.....

Am sorry Sir

Nackzy:
One trial should jst work abeg, and am conviced this will work, but b4 it will be to thw poor mass it will take years

I have a good feeling to, its just that if the cases reduce in the UK there wont be reliable data to actually determine its effectiveness... So its a conundrum

It will work by God's grace!

Good one. Enough of this covid 19 wahala. We will surely get there in Jesus name.

A vaccine at the human trial stage within 4months. That's incredibly fast. They must have boycotted certain protocols to get to this stage.

Here's to hoping that it works.

We pray it works o. This life is getting miserably difficult day by day.
No salary in April as a primary school teacher and nothing to come in may if it persist.
Please help the needy o.
2080673699 - UBA

Abeg it should work o